一条东部褐蛇
图片:Adobe
2022年6月20

Some of the world’s deadliest snakes could soon be saving lives, with research from OD电竞官方app showing venom could be used to stop uncontrolled bleeding.

The biomaterials research team OD电竞官方app的 Australian Institute for Bioengineering and Nanotechnology (AIBN), led by Postdoctoral 研究 Fellow 阿曼达Kijas, has found protein in the venom of two snakes – Australia’s eastern brown and scaled viper ­– could be used as an accelerant in the body’s natural blood-clotting process.

The team is working on a gel that could be sold in pharmacies, 添加到急救箱, and used by paramedics or military personnel in combat zones, to stop bleeding while a patient is taken to hospital.

The venom gel remains a liquid when stored in a cool place but solidifies at body temperature to seal the wound.

“As many as 40 per cent of trauma-related deaths are the result of uncontrolled bleeding, and this figure is much higher when it comes to military personnel with serious bleeding in a combat zone,基哈斯博士说.

“Nature has created the most elegant and sophisticated mechanisms, and we can repurpose them to save people from dying due to uncontrolled bleeding.

“The research shows there is five times less blood loss, and clots form three times more quickly when the venom gel is applied, compared to the body’s natural process.

“This even includes people with haemophilia and those using blood thinners.”

阿曼达Kijas 和博士生 拉马纳坦Yegappan looking at a computer in the lab.Dr Kijas, who worked alongside AIBN Director 教授艾伦•罗文名誉教授 马丁·拉文 和博士生 拉马纳坦Yegappan, said current first aid treatment using gauze products, often did not stop bleeding in an emergency.

“当创伤性伤害发生时, the complexity of the healing process overloads the body’s capacity to control the bleeding,基哈斯博士说.

“We hope this gel will accelerate the wound-healing processes needed for clotting and reducing blood flow, ultimately boosting the body’s capacity to heal large wounds.”

The study received funding from the United States Department of Defense, with blood donated from the Australian Red Cross Lifeblood.

The venom gel is being tested in pre-clinical evaluations and is being scaled-up toward commercial application in collaboration with 马克教授冬至 OD电竞官方app的 生物医学科学学院.

与北方大都会健康公司合作, at the Royal 布里斯班 and Women’s Hospital and Herston Biofabrication Institute, the research team is exploring how the technology could also treat burns and trauma injuries.

这项研究发表在 先进保健材料.

视觉和图像是可用的 通过Dropbox.

Image above left: 阿曼达Kijas 和博士生 拉马纳坦Yegappan conducting research in the lab.

阿曼达·基哈斯博士, a.kijas@fx-binary.net, +61 (0)435 267 618; Prof Alan Rowan 艾伦.rowan@fx-binary.net, +61(0)439 228 663,安娜爱德华兹, 安娜.edwards1@fx-binary.net, +61 (0)434 313 053.